Journal: EMBO Molecular Medicine

Article Title: Injury-induced intestinal stem cell renewal requires capillary morphogenesis gene 2

doi: 10.1038/s44321-025-00295-3

Figure Lengend Snippet: ( A ) Clusters of VISIUM spots coupled with tissue H&E staining, replotted from raw data published in Mayassi et al, 2024 (Data ref: Mayassi et al, ). ( B ) Cmg2 expression on intestinal tissue from VISIUM data, coupled with H&E staining. ( C ) frequency of VISUM spots expressing Cmg2 among clusters shown in ( A ). ( D ) RNAscope in situ hybridization of longitudinal sections of mice duodenum (top panel) or colon (bottom panel) for CMG2 (white) coupled with immunofluorescence staining of Olm4 (red), Keratin20 (green) and DAPI (blue). Representative images of n = 3 mice. ( E , F ) UMAP of scRNAseq replotted from raw data published in Mayassi et al, 2024 (Data ref: Mayassi et al, ). ( G ) Percentage of cells expressing Cmg2 from scRNAseq (Data ref: Mayassi et al, ).

Article Snippet: Figure EV3 Spatial transcriptomics of DSS-treated mice throughout the post-treatment recovery course for up to 73 days. ( A ) Clusters of VISIUM spots (upper panel) or Cmg2 expression (lower panel) coupled with tissue H&E staining, replotted from raw data published in Mayassi et al, 2024 (Data ref: Mayassi et al, ). ( B ) UMAP clustering of VISIUM data. ( C–E ) Ly6a ( C ), Cmg2 ( D ) and Lrp6 ( E ) expression on intestinal tissue from VISIUM data.

Techniques: Staining, Expressing, RNAscope, In Situ Hybridization, Immunofluorescence

Journal: EMBO Molecular Medicine

Article Title: Injury-induced intestinal stem cell renewal requires capillary morphogenesis gene 2

doi: 10.1038/s44321-025-00295-3

Figure Lengend Snippet: ( A ) Clusters of VISIUM spots (upper panel) or Cmg2 expression (lower panel) coupled with tissue H&E staining, replotted from raw data published in Mayassi et al, 2024 (Data ref: Mayassi et al, ). ( B ) UMAP clustering of VISIUM data. ( C–E ) Ly6a ( C ), Cmg2 ( D ) and Lrp6 ( E ) expression on intestinal tissue from VISIUM data.

Article Snippet: Figure EV3 Spatial transcriptomics of DSS-treated mice throughout the post-treatment recovery course for up to 73 days. ( A ) Clusters of VISIUM spots (upper panel) or Cmg2 expression (lower panel) coupled with tissue H&E staining, replotted from raw data published in Mayassi et al, 2024 (Data ref: Mayassi et al, ). ( B ) UMAP clustering of VISIUM data. ( C–E ) Ly6a ( C ), Cmg2 ( D ) and Lrp6 ( E ) expression on intestinal tissue from VISIUM data.

Techniques: Expressing, Staining